COVID-19 and Hypertension

https://jamanetwork.com/journals/jama/fullarticle/2763803 Coronavirus apparently has higher morbidity and mortality rates in people with hypertension, and this study posits why this might be. They believe that it might have to do with two medications used to treat hypertension: angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs). These both cause overexpression of angiotensin-converting enzyme 2 (ACE2), which … Read more

Considering cytokine storm syndromes and immunosuppression

Article Link: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30628-0/fulltext#articleInformation With the outbreak of a novel virus, antiviral treatments and vaccine development are at the forefront of research. This article urges the consideration of screening COVID-19 patients for signs of hyperinflammation which could signal that they are experiencing a so called “cytokine storm” in response to the virus. This has been seen … Read more

Literature Review: Identification of Potential COVID-19 Treatments

Article link: http://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/596/740 At this time, there are no FDA-approved treatments for COVID-19 and SARS-CoV-2 vaccines are still being developed or tested. By identifying potential COVID-19 treatments that are already approved for human use with other conditions, the expansive timeline for drug testing can become streamlined. Published on March 21 in the Archives of Academic … Read more